教 学 科 研 成 果 及 荣 誉 |
主持科研项目: 1．2011，国家自然科学基金，基因功能SNPs与DNA甲基化共同影响精神分裂症易感性机制研究，81071091. 2．2017．国家科技部，国家重点研发计划资助(2016YFC1306700)：抑郁障碍临床诊断、干预与转归的客观标记物研究（2016YFC1306704），2016 年07 月 —— 2020 年12 月，77万元 课题四：MDD发病和复发风险评估模型及诊断工具包开发应用. 3．2015．国家自然科学基金，电休克刺激对SD大鼠脑中枢神经系统可塑性的影响（81571315），2016.01-2017.12. 4．2017，国家自然科学基金-河南省联合基金重点培育项目。多维度关联分析脑白质功能相关基因筛选精神分裂症生物学标记(U1704190)，L02，2018.01.01-2020.12.31. 5．2011，新世纪优秀人才支持计划，基于全基因组DNA甲基化筛选基础上的精神分裂症患者目的基因甲基化状态检测，NCET-10-0137. 6．2019，中共河南省委组织部，河南省人力资源和社会保障厅 中原千人计划-中原科技创新领军人才。基于认知图式的冷执行功能训练对抑郁症患者的康复作用及脑影像学机制204200510020，2020.01.01-2022.12.31. 7．2018 河南省科技创新人才（杰出青年）计划174100510024，基于汇聚功能基因组学信息建立精神分裂症遗传影像学联合诊断标记. 2017.01-2018.12, 30万. 8．2010，河南省科技厅发展计划，基因功能SNPs与DNA甲基化共同影响精神分裂症易感性机制研究，102102310153. 9．2008，河南省科技厅发展计划，Neuregulin-1基因多态性及其功能表达与精神分裂症，08210230081. 10．2010，河南省高校青年骨干教师，候选基因甲基化状态与精神分裂症的关联研究，2010GGJS-116. 11．2010，河南省教育厅自然科学基金，基因组DNA甲基化水平与精神分裂症关联研究，2010A320014. 12．2012.01-2013.01精神分裂症患者主动式社区康复模式探索，河南省卫生厅，5.0. 13．2013－01－2015.12 河南省卫生厅 河南卫生科技创新型人才工程优秀人员项目，精神疾病全基因组关联分析与药物基因组学研究（cxyx20130418）. 14．2014，主动式社区康复模式下慢性精神疾病患者心理干预模式探索，2014-GH-643 完成时间：2015.04. 15．2015,河南省科技厅，电休克剌激对精神分裂症模型大鼠脑神经元网络振荡的影响，（152300410122），2015.01-2017.12. 5万元. 16．2016，PN-KFKT-10 张红星 多维度关联分析脑白质功能相关基因筛选精神分裂症生物学标记，精神神经研究院开放课题,10万元. 17．2017年申报，河南省高校科技创新团队，精神疾病认知生理心理机制研究团队（18IRTSTHN025）：2018.01-2019.12. 发表SCI期刊论文： 1．Hong-Xing Zhang, Zhao JP, Lv LX, Li WQ, Xu L, Ouyang X, Yuan ZQ, Huang JS. Explorative study on the expression of neuregulin-1 gene in peripheral blood of schizophrenia. Neuroscience letters 2008 24(5):1-5.（IF=2.2）ISSN:0304-3940 2．Li W, Wang X, Zhao J, Lin J, Song X, Yang Y, Jiang C, Xiao B, Yang G, Zhang H*（通讯作者）, Lv L*. Association Study of myelin transcription factor 1-like polymorphisms with schizophrenia in Han Chinese population. Genes Brain Behav. 2012 Feb;11(1):87-93.. （IF=4.061）ISSN:1601-1848 3．Liang Gong, Yingying Yin, Cancan He, Qing Ye, Feng Bai,Yonggui Yuan, Haisan Zhang, Luxian Lv, Hongxing Zhang*, Chunming Xie*, Zhijun Zhang. Disrupted reward circuits is associated with cognitive deficits and depression severity in major depressive disorder. Journal of Psychiatric Research. 2017 Jan;84:9-17. ISSN:0022-3956（IF=4.465） 4．Yi Yu, Yun Zhao, Yajing Si, Qiongqiong Ren, Wu Ren, Changqin Jing and Hongxing Zhang*. Estimation of the cool executive function using frontal electroencephalogram signals in first‑episode schizophrenia patients. BioMed Eng OnLine 2016 Nov 25;15(1):131-145 ISSN: 1475-925X (IF=1.682) 5．Liang Gong, Cancan He, Haisan Zhang, Hongxing Zhang*, Zhijun Zhang, Chunming Xie*. Disrupted reward and cognitive control networks contribute to anhedonia in depression, Psychiatry research. J Psychiatr Res. 2018 Aug;103:61-68. doi: 10.1016/j.jpsychires.2018.05.010. Epub 2018 May 12. 6．He C, Gong L, Yin Y, Yuan Y, Zhang H, Lv L, Zhang X, Soares JC, Zhang H*, Xie C, Zhang Z. Amygdala connectivity mediates the association between anxiety and depression in patients with major depressive disorder. Brain Imaging Behav. 2019;13(4):1146-1159. doi: 10.1007/s11682-018-9923-z.IF=3.391 7．Li, K., Zhang, H., Wang, B., Yang, Y., Zhang, M., Li, W., Li, X., Lv, L., Zhao, J., & Zhang, H*. (2020). Hippocampal functional network: The mediating role between obsession and anxiety in adult patients with obsessive-compulsive disorder. The world journal of biological psychiatry., 2020 Nov;21(9):685-695. doi: 10.1080/15622975.2020.1733082. Epub 2020 Mar 16. IF2020=4.132 8．Kun Li# , Haisan Zhang# , Yongfeng Yang, Jianli Zhu , Bi Wang , Yanli Shi , Xianrui Li,,Meng Zhang, Luxian Lv ⁎, Hongxing Zhang*, Abnormal functional network of the thalamic subregions in adult patients with obsessive-compulsive disorder, Behavioural Brain Research, 2019 May 26;371:111982. IF=3.327 ISSN : 0166-4328 9．Xianrui Li, Meng Zhang, Kun Li, Feng Zou, Yufeng Wang, Xin Wu and Hongxing Zhang* The Altered Somatic Brain Network in State Anxiety. Frontier in Psychiatry.2019,07 IF=3.161 ISSN: 1664-0640 10．Haisan Zhang, Bi Wang, Kun Li, Xiaoyue Wang, Xianrui Li, Jianli Zhu, Qingjiang Zhao, Yongfeng Yang, Luxian Lv, Meng Zhang and Hongxing Zhang*.Altered Functional Connectivity Between the Cerebellum and the Cortico-Striato-Thalamo-Cortical Circuit in Obsessive-Compulsive Disorder. Frontier in Psychiatry. 2019．07， 10:522 P1-8. IF=3.161 ISSN: 1664-0640 11．Li K, Zhang M, Zhang H, Li X, Zou F, Wang Y, Wu X, Zhang H*.The spontaneous activity and functional network of the occipital cortex is correlated with state anxiety in healthy adults. Neurosci Lett. Neurosci Lett. 2020;715:134596. doi:10.1016/j.neulet.2019.134596 IF2020=3.046 12．Zhijun Zhang #, Hongxing Zhang # , Chun-Ming Xie # , Meng Zhang # , Yachen Shi , Ruize Song , Xiang Lu , Haisan Zhang , Kun Li , Bi Wang , Yongfeng Yang , Xianrui Li , Jianli Zhu , Yang Zhao , Ti-Fei Yuan , Georg Northoff. Task-related functional magnetic resonance imaging-based neuronavigation for the treatment of depression by individualized repetitive transcranial magnetic stimulation of the visual cortex. Sci China Life Sci. 2021 Jan;64(1):96-106. IF=6.03 13．Xinyi Liu , Cancan He , Dandan Fan , Yao Zhu , Feifei Zang , Qing Wang , Haisan Zhang , Zhijun Zhang , Hongxing Zhang *, Chunming Xie * Disrupted rich-club network organization and individualized identification of patients with major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2020 Aug 18;110074. IF=4.263 14．Xiaoxiao Shan Haisan Zhang Zhao Dong Chen Feng Liu5 Jingping Zhao Hongxing Zhang* Wenbin Guo. Increased subcortical region volume induced by electroconvulsive therapy in patients with schizophrenia. European Archives of Psychiatry and Clinical Neuroscience. 2021 Oct;271(7):1285-1295. doi: 10.1007/s00406-021-01303-6. Epub 2021 Jul 17. IF2021=5.760 15．Tong W, Dong Z, Guo W, Zhang M, Zhang Y, Du Y, Zhao J, Lv L, Liu Y, Wang X, Kou Y, Zhang H, Zhang H*. Progressive Changes in Brain Regional Homogeneity Induced by Electroconvulsive Therapy Among Patients With Schizophrenia. J ECT. 2022 Jun 1;38(2):117-123. doi: 10.1097/YCT.0000000000000815. PMID: 35613010. IF= 3.692 ISSN：1095-0680 16．Liu Y, Zhang J, Zhang M, Li X, Li K, Wang B, Yang Y, Song R, Si Y, Ni T, Wang X, Geng Y, Chang Q, Zhang H, Zhang Z, Zhang H*. Abnormal brain gray matter volume in patients with major depressive disorder: Associated with childhood trauma? J Affect Disord. 2022 Apr 20;308:562-568. (IF2022=6.533) ISSN：0165-0327 17．Si Y, Liu C, Kou Y, Dong Z, Zhang J, Wang J, Lu C, Luo Y, Ni T, Du Y, Zhang H.Antipsychotics-induced improvement of cool executive function in individuals living with schizophrenia. Front Psychiatry. 2023 Apr 27;14:1154011. 18．Si Y, Li P, Wang X, Yao G, Liu C, Liu Y, Zhang J, Zhang H, Luo Y. Cueing effect of attention among nurses with different anxiety levels: an EEG study. Med Biol Eng Comput. 2023 Mar 29. |
