程彬峰,男,1985年出生。博士,副教授,硕士研究生导师。
联系方式
E-mail:chengbinfeng@xxmu.edu.cn
教育与工作经历
2013.07---至今437必赢会员中心,生命科学技术学院,应用神经科学研究所
2008.09-2013.06 南开大学,药学院,博士(硕博连读)
2004.09-2008.07河南师范大学,生命科学学院,学士
研究方向
神经炎症与保护;干细胞分化与治疗;中药抗炎与免疫
项目课题
1、国家自然基金青年基金项目,基于VEGF/MAPK/FAK通路调控的风湿骨痛胶囊通络止痛的机制研究,81403161,2015.01-2017.12,主持。
2、河南省高等学校重点科研项目,NCAM抑制MSCs软骨肥大的作用及其治疗骨关节炎的开发应用研究,19A310020,2019.01-2020.12,主持。
3、437必赢会员中心博士启动基金,神经细胞粘附分子对骨髓间充质干细胞向软骨分化的调控作用及机制,主持。
代表性成果
1、Gao YX, Yu HH, He C, Li M, Guo DD, Lian JJ, Yang HJ, Wang M, Wang L*, Feng ZW, Cheng BF*. Fengshi Gutong capsule attenuates osteoarthritis by inhibiting MAPK, NF-κB, AP-1, and Akt pathways. Front Pharmacol, 2018, 9:910.
2、Ma J, Gao SS, Yang HJ, Wang M, Cheng BF*, Feng ZW, Wang L*. Neuroprotective effects of proanthocyanidins, natural flavonoids derived from plants, on rotenone-induced oxidative stress and apoptotic cell death in human neuroblastoma SH-SY5Y cells. Front Neurosci, 2018, 12:369.
3、Cheng BF, Gao YX, Lian JJ, Guo DD, Liu TT, Xie YF, Wang L, Yang HJ, Wang M*, Feng ZW. Anti-inflammatory effects of pitavastatin in interleukin-1β-induced SW982 human synovial cells. Int Immunopharmacol, 2017, 50:224-229.
4、Yao-Xin Gao, Bin-Feng Cheng*, Jun-Jiang Lian, Dan-Dan Guo, Jing-Wen Qin, Yong-Bo Zhang, Hai-Jie Yang, Mian Wang, Lei Wang*, Zhi-Wei Feng.Liquiritin, a flavone compound from licorice, inhibits IL-1β-induced inflammatory responses in SW982 human synovial cells. J Funct Foods, 2017, 33: 142-148.
5、Bin-Feng Cheng, Yao-Xin Gao, Jun-Jiang Lian, Dan-dan Guo, Lei Wang*, Mian Wang, Hai-Jie Yang* and Zhi-Wei Feng. Hydroxysafflor yellow A inhibits IL-1β-induced release of IL-6, IL-8, and MMP-1 via suppression of ERK, NF-κB and AP-1 signaling in SW982 human synovial cells. Food Funct, 2016, 7: 4516-4522.
6、Jun-Jiang Lian, Bin-Feng Cheng*, Yao-Xin Gao, Han Xue, Lei Wang, Mian Wang, Hai-Jie Yang, Zhi-Wei Feng*. Protective effect of kaempferol, a flavonoid widely present in varieties of edible plants, on IL-1β-induced inflammatory response via inhibiting MAPK, Akt, and NF-κB signalling in SW982 cells. J Funct Foods, 2016, 27: 214-222.
7、连俊江,程彬峰*,高尧鑫,张亚平,马双平,张彬彬,郭丹丹,薛寒,冯志伟。齐墩果酸对IL-1β诱导的SW982细胞炎症反应的抑制作用。药学学报,第51卷,第11期,1711-1716页。