郭春磊,1983.09-,南开大学理学博士学位。2017年至今就职于437必赢会员中心医学检验学院,目前的研究方向为肿瘤免疫,主要从事肿瘤干细胞与肿瘤微环境之间相互调控的分子机制及肿瘤转移和复发过程的机制研究。累计主持国家自然科学基金1项,河南省高校重点科研项目1项;在Theranostics、International Journal of Pharmaceutics、Scientific Reports等杂志上发表论文5篇。
发表SCI论文一览表(#为第一作者,*为通讯作者) Guo C#, Chen Y#, Gao W, Chang A, Ye Y, Shen W, Luo Y, Yang S, Sun P, Xiang R*, Li N*. Liposomal Nanoparticles Carrying anti-IL6R Antibody to the Tumour Microenvironment Inhibit Metastasis in Two Molecular Subtypes of Breast Cancer Mouse Models. Theranostics. 2017 Jan 26;7(3):775-788. IF=8.854 Hou J, Guo C, Shi Y, Liu E, Dong W, Yu B, Liu S, Gong J. A novel high drug loading mussel-inspired polydopamine hybrid nanoparticle as a pH-sensitive vehicle for drug delivery. Int J Pharm. 2017 Nov 25;533(1):73-83. IF= 3.649 Zhen Y, Chunlei G, Wenzhi S, Shuangtao Z, Na L, Rongrong W, Xiaohe L, Haiying N, Dehong L, Shan J, Xiaoyue T*, Rong X*. Clinicopathologic significance of legumain overexpression in cancer: a systematic review and meta-analysis. Sci Rep. 2015 Nov 26;5:16599. IF= 5.228 Zhen Y, Xinghui Z, Chao W, Yi Z, Jinwen C, Ruifang G, Chao Z, Min Z, Chunlei G, Yan F, Lingfang D, Long S, Wenzhi S, Xiaohe L, Rong X. Several microRNAs could predict survival in patients with hepatitis B-related liver cancer. Sci Rep. 2017 Mar 21;7:45195. IF= 5.228 Shen W#, Xie J#, Zhao S, Du R, Luo X, He H, Jiang S, Hao N, Chen C, Guo C, Liu Y, Chen Y, Sun P, Yang S, Luo N, Xiang R*, Luo Y*. ICAM3 mediates inflammatory signaling to promote cancer cell stemness. Cancer Lett. 2018 May 28;422:29-43. IF= 6.375
主持的重大科研项目: FBF1促进乳腺癌细胞干性和侵袭转移的机制研究,郭春磊,国家自然科学基金2019.01-2021.12,No. 81802967,21万元。
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